Bromocriptine : Uses, Side Effects & Interactions

Uses

For the treatment of Parkinson’s disease, Bromocriptine is used alone or with other medications (such as Livodopa). It can improve the ability to move and reduce weakness (shudder), rigidity, slow movement, and instability. It may not be able to reduce the number of episodes (“on-off syndrome”).

Bromocriptine is also used to treat high levels of a fixed hormone made by the body (prolactin). High levels of prolactin can cause problems like unwanted breast milk, missed / stops for periods, difficulty in getting pregnant, decrease in sperm production, and decreased sexual capacity. Bromocriptine can be used to treat tumors which cause high levels of prolactin (prolactin-secreting adenomas). It can help to reduce tumor size. Bromocriptine is not recommended to prevent unwanted breast milk after pregnancy, miscarriage or abortion, due to potential severe side effects (such as high blood pressure, seizure, heart attack, stroke).

Bromocriptine is also used for the treatment of high-level growth hormone (acromegaly).

Bromocriptine is an ergot drug that works by acting like a certain natural substance (dopamine) in the brain. It also prevents the release of some hormones (growth hormone, prolactin). Bromocriptine can reduce the level of hormones, but it does not cure the causes of increased levels.

How To Use Bromocriptine MESYLATE

Take this medicine with your doctor’s prescribed mouth, usually 1 or 2 times daily. Dosage is based on your medical condition and response to treatment. Due to the treatment of acromegaly, dose growth is also based on the level of hormones. To reduce your risk of side-effects, your doctor may direct you to start this medication on low dose and gradually increase your dose. Follow your doctor’s instructions carefully.

Take this medication regularly to get the most benefits from this. To help you remember, take it every day at the same time.

Do not stop this medicine without consulting your doctor. When this drug suddenly stops, some conditions may worsen even more. In addition, you may experience symptoms such as fever, muscle rigidity and delusion. To prevent these symptoms during your treatment with this drug, your doctor may gradually reduce your dose. Contact your doctor or pharmacist for more information. Report any new or worse symptoms instantly.

Tell your doctor if your condition does not improve or it gets worse.

Side Effects

Nausea, vomiting, dizziness, drowsiness, mildness, fatigue, constipation, or headache can occur. If any of these effects is persistent or worse, tell your doctor or pharmacist immediately.

Remember that your doctor has prescribed this medicine because it has decided that your benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.

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Some people who take bromocriptine have suddenly slept during their usual daily activities (such as talking on the phone, driving). In some cases, sleep without first feeling of sleep This sleep effect may occur at any time during treatment of bromocriptine, even if you have used this medicine for a long time. If you increase sleep during the day or sleep, do not participate or take part in other potentially hazardous activities unless you discuss this effect with other doctors. By using alcohol or other medicines, your risk of the effect of this sleep increases, which can put you in sleep. See also the Precautions section.

This medicine can increase or decrease your blood pressure. Monitor your blood pressure guided by your doctor. A decrease in blood pressure usually occurs when you are starting a medication for the first time, when your dose increases, or when you wake up suddenly. This effect can cause dizziness, lightness, and tilt. To reduce the risk of dizziness and lightness, get up slowly from the position of sitting or lying.

If you have any serious side effects, immediately ask your doctor: back pain, feet / ankle / swelling of the feet, symptoms of kidney problems (like changes in urine volume), persistent nose, severe stomach / stomach Pain, black / bloody stool, vomiting coffee ground, cold or slightly blue fingers / toes, hands / feet tilt / haze, change in mental / mood (like anxiety, confusion, hallucinations, restlessness) Normal strong request (such as increased gambling, increased sexual harassment), slow / fast / irregular heartbeat.

If you have any serious side effects, get immediate medical assistance, including: severe or persistent headache, seizure, difficulty speaking, weakness on one side of the body, changes in vision (such as decrease / blurred vision), chest / jaw / Left hand pain, trouble breathing.

A very serious allergic reaction to this drug is rare. However, if you see any symptoms of severe allergic reactions, get immediate medical help, including: tooth, itching / swelling (especially the face / tongue / throat), severe dizziness, breathing Trouble.

This is not a complete list of potential side effects. If you see other effects not listed above, contact your doctor or pharmacist.

Precautions

Before taking bromocriptine, tell your doctor or pharmacist if you are allergic to it; Or for other ergot drugs (eg ergotamine, pergolide); Or if you have any other allergies. This product may have passive elements, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

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Before using this drug, tell your doctor or pharmacist your medical history, especially: some genetic enzyme problems (galactose intolerance, lactase deficiency, glucose-galactose malabsorption), high or low blood pressure, liver disease, heart (Such as coronary artery disease, heart attack, irregular heart beat), mental / mood disorders (such as psychology, depression, schizophrenia) Bleeding freight / intestinal problems (eg, ulcers), problems with blood flow (such as peripheral vascular disease, Raynaud’s disease), recently with high blood pressure during pregnancy (specifically).

This drug may make you dizzy or drowsy. Alcohol or marijuana can make you feel more dizzy or sleepy. Do not drive, do not use machinery, or do anything that requires caution unless you can safely do it. Avoid alcoholic beverages. If you are using marijuana, talk to your doctor. See also the Side Effects section.

Bromocriptine can reduce blood flow to the fingers and toes, especially in exposure to cold, increase the risk of damage (e.g. frostbite). Keep warm and warm feet in the cold weather.

Before performing the surgery, tell your doctor or dentist about all the products (including prescription drugs, non-prescription medicines and herbal products).

During pregnancy, this drug should be used only if it is clearly required. During pregnancy, this drug can increase the risk of blood pressure. Discuss the risks and benefits with your doctor.

Since this drug can restore fertility in women with high prolactin or growth hormone, women who do not want to become pregnant, while taking this medication they will be treated with non-hormonal birth control methods (like condom, diaphragm) Should discuss the use of At least one pregnancy test is recommended every 4 weeks before your period starts again. If you start your period regularly, then every time you remember your period, pregnancy test is recommended. If you become pregnant or think that you can get pregnant then immediately ask your doctor.

This drug can affect breast milk production. Therefore, breastfeeding is not recommended when using this drug. Consult your doctor before breastfeeding.

Interaction

Drug interactions can change how your medicines work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescriptions / non-prescription medicines and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change any drug dosage without your doctor’s approval.

Some medicines that can interact with this drug include: antipsychotic drugs (such as chlorpromazine, haloperidol, thioridazine), other  ergot medicines (such as  ergotamine), “triptans” (such as sumatriptan, frovatriptan).

Other medicines can affect the removal of bromocriptine from your body, which can affect how bromocriptine works. Examples include azole antifungal (such as intraconazole, ketokonazole), Boceprevir,  delavirdine, macrolide antibiotics (such as clarithromycin, erythromycin), nefazodone, HIV protease inhibitors (such as lopinavir, ritonavir), telaprevir, telithromycin.

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Tell your doctor or pharmacist that if you are taking other products that are alcoholic, marijuana, antihistamine (such as cetirizinediphenhydramine), sleep or anxiety (such as alprazolam, diazepam, zolpidem), resting muscles (such as carisoprodolcyclobenzaprine ), And narcotic pain relief (eg, codeine, hydrocodone).

Check the label on all your medications (like allergy or cough and cold products) because they may contain elements that cause drowsiness. Ask your pharmacist about using those products safely.

Overdose

If someone has entered a greater amount and has serious symptoms like having difficulty passing or breathing, call 911. Otherwise, call the Poison Control Center immediately. American residents can call their local poison control center at 1-800-222-1222. Canadian residents can call a provincial poison control center. Significant symptoms may include: changes in mental / mood (such as hallucinations, agitation, confusion), severe dizziness, tilt

Notes

Do not share this medication with others.

Labs and / or medical tests (such as blood pressure, kidney / liver function, eye examinations, full blood count) should be periodically monitoring your progress or checking side effects. Consult your doctor for more details.

People with Parkinson’s disease can increase risk for developing skin cancer (melanoma). If you are taking this medicine for the treatment of Parkinson’s disease, then if you see a change in appearance or mole size or other unusual skin change, then ask your doctor immediately. If you have a regular skin examination, ask your doctor.

Missed dose

If you miss the dose, then as soon as you miss it. If it is near the next dose time, then leave the immersed dose and start your normal dose schedule again. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush the medicines under the toilet or put them in the groove unless instructed to do so. When properly finished this product is discarded or it is not required. Consult your pharmacist or local waste disposal company.

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