Xibrom : Uses, Side Effects, Interactions & More

Why is this medication prescribed?

Xibrom (Bromfenac) ophthalmic is used to treat the swelling and redness (inflammation) of the eyes and pain that can occur after cataract surgery. Xibrom ophthalmic is in a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It works by stopping the release of certain natural substances that cause pain and swelling.

How should this medicine be used?

Xibrom (Bromfenac) ophthalmic comes as a solution (liquid) to instill into the eyes. It is usually instilled into the affected eyes once or twice a day for 14 days after cataract surgery. Your doctor may also instruct you to use Xibrom the day before and on the day of surgery, depending on the brand of Xibrom ophthalmic that your doctor has prescribed. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any parts you do not understand. Use Xibrom ophthalmic exactly as directed. Do not use more or less or use it more often than prescribed by your doctor.

To instill the eye drops, follow these steps or the information the manufacturer has provided with the product:

  1. Wash your hands well with soap and water.
  2. Check the dropper tip to make sure it is not chipped or cracked.
  3. Avoid touching the tip of the dropper against your eye or anything else; eye drops and droppers must be kept clean.
  4. While tilting your head back, lower the lower lid of your eye with your index finger to form a pocket.
  5. Hold the dropper (tip down) with the other hand, as close to the eye as possible without touching it.
  6. Rest the remaining fingers of that hand against your face.
  7. While looking up, gently squeeze the dropper so that a single drop falls into the pocket formed by the lower eyelid. Remove your index finger from the lower eyelid.
  8. Close your eye for 2 to 3 minutes and tilt your head down as if looking at the ground. Try not to blink or squeeze your eyelids.
  9. Place a finger over the tear duct and apply gentle pressure.
  10. Wipe any excess fluid from your face with a tissue.
  11. Replace and tighten the dropper bottle cap. Do not clean or rinse the dropper tip.
  12. Wash your hands to remove any medicine.

Each bottle of eye drop solution should be used for one eye only. If both of your eyes need to have treatment, you should have a separate bottle for each eye.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before using Xibrom eye drops,

  • Tell your doctor and pharmacist if you are allergic to Xibrom Ophthalmic, aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs), any other medications, sulfite, or any of the ingredients in Xibrom eye drops. Ask your pharmacist for a list of the ingredients.
  • Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: anticoagulants (‘blood thinners’) such as warfarin (Coumadin); aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, Midol) and naproxen (Aleve, Naprosyn); steroid products that are applied to the eyes such as dexamethasone (Maxidex, in Dexasporin, Maxitrol, Tobradex), difluprednate (Durezol), fluorometholone (Flarex, FML) ,lotprednol (Alrex, Lotemax, Zylet) and prednisolone (Omnipred, Pred Forte, Pred Mild, in Blephamide, Pred-G); (NSAIDs) ,.
  • If you are using another eye drop medicine, use the eye medicine at least 5 minutes apart.
  • Tell your doctor if you have or have ever had diabetes, asthma, rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), dry eye disease, or any eye problems other than cataracts, any condition that makes you bleed easily, or if you have recently had eye surgery on the same eye that is being operated on.
  • Tell your doctor if you wear contact lenses. You must remove your contact lenses before applying Xibrom eye drops and wait at least 10 minutes after using the medication to replace your lenses.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
  • You should know that Xibrom eye drops may delay the healing of the eye after surgery. Call your doctor right away if pain and swelling do not improve.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?

Instill the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not give a double dose to make up for a missed one.

What side effects can this medication cause?

Xibrom eye drops may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • stinging or burning of the eyes
  • red or itchy eyes
  • feeling that something is in the eye
  • headache

Some side effects can be serious. If you experience any of these symptoms, stop using Xibrom eye drops and call your doctor immediately:

  • redness or swelling of eyes, lips, tongue, or skin
  • rash, hives, or other skin changes
  • difficulty breathing or swallowing
  • bleeding within the eye
  • sensitivity of your eyes to light
  • eye pain
  • blurry, cloudy, or blocked areas of vision

If you experience a serious side effect, you or your doctor can submit a report online to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medicine in the container it came in, tightly closed, and out of the reach of children. Store at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medicines out of the sight and reach of children, since many containers (such as those containing weekly pills and those for eye drops, creams, patches and inhalers) are not resistant to children and small children can easily open them. To protect young children from poisoning, always close the safety caps and immediately place the medicine in a safe place, one that is upright and out of their sight and reach. http://www.upandaway.org

Unnecessary medications must be disposed of in special ways to ensure that pets, children, and others cannot consume them. However, you should not flush this medicine down the toilet. Instead, the best way to dispose of your medications is through a drug take-back program. Talk to your pharmacist or contact your local garbage / recycling department to find out about take-back programs in your community. See the FDA Safe Drug Disposal website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of emergency/overdose

If someone ingests Xibrom eye drops, call your local poison control center at 1-800-222-1222. If the victim has passed out or is not breathing, call your local emergency services at 911.

What other information should I know?

Keep all your appointments with your doctor.

Don’t let anyone use your medicine.

It is important that you keep a written list of all prescription and over-the-counter (over-the-counter) medications you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should take this list with you each time you visit a doctor or if you go into hospital. It is also important information to take with you in case of emergencies.

Brand Names

  • Bromday®
  • Bromsite®
  • Prolensa®
  • Xibrom®

Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.

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