Provera : Uses, Side Effects, Interactions & More
Why is this medication prescribed?
Provera (Medroxyprogesterone) is used to treat abnormal menstruation (periods) or irregular vaginal bleeding. Provera is also used to provoke a normal menstrual cycle in women who have menstruated normally in the past, but who have not menstruated for at least 6 months and who are not pregnant or at the stage of menopause (life change). Provera is also used to prevent overgrowth of the lining of the uterus (womb) and may decrease the risk of uterine cancer in patients who are taking estrogen. Provera belongs to a class of medications called progestins. It works by stopping the growth of the lining of the uterus and by causing the uterus to make certain hormones.
How should this medicine be used?
Provera (Medroxyprogesterone) comes as a tablet to take by mouth. It is usually taken once a day on certain days of a normal monthly cycle. To help you remember to take Provera, take it at about the same time each day on the days you need to take it. Follow the instructions on your prescription label carefully and ask your doctor or pharmacist for explanations about any part you do not understand. Take Provera exactly as directed. Do not take more or less or take it more often than prescribed by your doctor.
Provera (Medroxyprogesterone) can control your condition, but it does not cure it. Continue to take Provera on your monthly schedule even if you feel well. Do not stop taking Provera without talking to your doctor.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking Provera,
Tell your doctor and pharmacist if you are allergic to Provera (medroxyprogesterone) (Provera, Depo-Provera), any other medications, or corn.
Tell your doctor and pharmacist what prescription and over-the-counter medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention aminoglutethimide (Cytadren). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have or have ever had cancer of the breast or female organs; unexplained vaginal bleeding; a missed abortion (a pregnancy that ended when the fetus died in the womb but was not expelled from the body); blood clots in your legs, lungs, brain, or eyes; race or mini race; seizures migraines; depression; asthma; diabetes; or heart, kidney, or liver disease.
Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking Provera, call your doctor immediately. Provera should never be used to assess pregnancy or to prevent miscarriage during the first months of pregnancy. Provera has not been shown to prevent miscarriage and may harm the fetus.
If you are going to have surgery, including dental surgery, tell the doctor or dentist that you are taking Provera.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed dose.
What side effects can this medication cause?
Provera may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- breasts that are tender or produce a liquid
- changes in menstrual flow
- growth of hair on face
- loss of hair on scalp
- difficulty falling asleep or staying asleep
- upset stomach
- weight gain or loss
- irregular vaginal bleeding or spotting
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
- pain, swelling, warmth, redness, or tenderness in one leg only
- slow or difficult speech
- dizziness or faintness
- weakness or numbness of an arm or leg
- shortness of breath
- bulging eyes
- missed periods
- yellowing of the skin or eyes
- skin rash
- difficulty breathing or swallowing
- swelling of the hands, feet, ankles, or lower legs
- coughing up blood
- sudden sharp or crushing chest pain
- fast or pounding heartbeat
- sudden vision changes or loss of vision
- double vision
- blurred vision
Some laboratory animals that received Provera developed breast tumors. It is not known whether Provera increases the risk of human breast cancer. Provera may also increase the chance that a blood clot will develop and move to the lungs or brain. Talk to your doctor about the risks of taking this medication.
Provera (Medroxyprogesterone) can cause other side effects. Call your doctor if you have any unusual problems while taking this medicine.
If you experience a serious side effect, you or your doctor can submit an online report to the Food and Drug Administration (FDA) MedWatch Adverse Event Reporting Program (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about storage and disposal of this medication?
Keep this medicine in its container, tightly closed and out of the reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unnecessary medications must be disposed of in special ways to ensure that pets, children, and others cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to get rid of your medication is through a medication take-back program. Talk to your pharmacist or contact your local garbage / recycling department for information on return programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medications out of the sight and reach of children, as many containers (such as those for taking pills weekly and those used for eye drops, creams, patches and inhalers) are not resistant to children and children. young children can easily open them. To protect young children from poisoning, always close the safety caps and immediately put the medicine in a safe place, one that is up and away and out of your sight and reach. http://www.upandaway.org
In case of emergency/overdose
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.
Do not share this medicine with others.
Keep all appointments with your doctor and the laboratory. You should have a complete physical exam that includes blood pressure measurements and sinus / pelvic exams at regular intervals (like once a year) or as directed by your doctor. Follow your doctor’s instructions on how to examine your own breasts and report any lumps immediately. You should also be screened for cervical cancer regularly (for example, by a Pap test) and have regular mammograms as determined by your doctor. Check with your doctor for more details.
Store at room temperature, between 15 and 30 degrees C (59 and 86 degrees F), protected from light and moisture. Do not store in the bathroom. Keep all medications out of the reach of children and pets.
Do not flush medications down the toilet or pour them down a drain unless instructed to do so. Properly dispose of this product when it expires or is no longer needed. Consult your pharmacist or local waste disposal company for more details on how to safely dispose of your product.
What other information should I know?
Keep all your appointments with your doctor.
Before having a laboratory test, tell your doctor and the laboratory personnel that you are taking Provera.
Do not let anyone else take your medicine. Ask your pharmacist any questions you have about refilling your prescription.
It is important that you keep a written list of all prescription and over-the-counter (non-prescription) medications you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should carry this list with you every time you visit a doctor or if you are admitted to a hospital. It is also important information to take with you in emergencies.
Brand names of combination products
- Premphase® (containing Medroxyprogesterone Acetate and Conjugated Estrogens)
- Prempro® (containing Medroxyprogesterone Acetate and Conjugated Estrogens)
Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.